Heading south, take the Denny Way exit to the right. Turn right on Denny. Follow Denny past the Pacific Science Center to the stoplight at Denny and Queen Anne Ave, approximately .75 miles (Shell gas station on the right hand corner). Looking straight ahead and slightly to the left, you will see the dark grey NW WorkLofts Building (U-shape building with greenery in the center). Seattle Aesthetics is located on the street level of that U-shaped building where Denny St. turns into Western Ave. Signage is clearly marked on the street-front windows.
Continue on Denny Ave and at the second light, make an immediate right up the alley to the U-Park lots. It comes up fairly quickly so it may be easier to circle around the block and access the alley from the back side of the block. To circle back around the block, take the first right (after the alley) on 1st Ave W, turn right at the next block (John St.) and then turn right into the alley. There are two parking lots accessible from this alley. You can also look for street parking along Western Ave.